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One-Pan Chicken

One-Pan Herb-Crusted Turkey Breast with Roasted Brussels Sprouts and Cranberries

By PanPotPlates Test KitchenReviewed by PanPotPlates Editorial TeamPublished Apr 30, 2026 · Updated May 12, 2026
American-Inspired 55 mins onepaneasyfamilydinnerhealthyseasonalholidayglutenfreedairyfreebudget-friendlyroastedleftovers

A flavorful, easy, and healthy one-pan recipe featuring herb-crusted roasted turkey breast with caramelized Brussels sprouts and fresh cranberries. Perfect for family dinners, holiday meals, and meal prepping with minimal cleanup.

One-Pan Herb-Crusted Turkey Breast with Roasted Brussels Sprouts and Cranberries
Prep 15 min
Cook 40 min
Total 55 min
Servings 6
Difficulty easy
Cuisine American-Inspired

Recipe Details

Prep15 min
Cook40 min
Total55 min
Servings6
Difficultyeasy
CuisineAmerican-Inspired
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Ingredients

Servings 6
  • 1 (2 to 3-pound) boneless turkey breast, skin-on
  • 2 tablespoons olive oil, divided
  • 2 teaspoons garlic powder
  • 2 teaspoons dried thyme
  • 2 teaspoons dried rosemary
  • 1 teaspoon dried sage
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1 pound Brussels sprouts, trimmed and halved
  • 1 cup fresh cranberries
  • 1 tablespoon balsamic vinegar
  • 1 teaspoon honey or maple syrup (optional)
  • Fresh parsley, chopped (for garnish)

Instructions

  1. Preheat oven to 400°F (200°C).
  2. Mix garlic powder, dried thyme, rosemary, sage, salt, and black pepper in a small bowl.
  3. Pat turkey breast dry with paper towels. Rub 1 tablespoon olive oil over turkey, then evenly coat with herb seasoning.
  4. Place turkey breast in center of large rimmed baking sheet or sheet pan.
  5. Toss halved Brussels sprouts with remaining 1 tablespoon olive oil and a pinch of salt and pepper in a medium bowl.
  6. Arrange Brussels sprouts evenly around turkey on the pan.
  7. Scatter fresh cranberries over and around the Brussels sprouts.
  8. Whisk balsamic vinegar with honey or maple syrup (if using) and drizzle over vegetables.
  9. Roast for 35-40 minutes, until turkey reaches internal temperature of 165°F (74°C) and Brussels sprouts are tender and caramelized.
  10. Remove from oven and rest turkey breast 5-10 minutes before slicing.
  11. Garnish turkey and vegetables with chopped fresh parsley. Serve warm.
  12. Store leftovers in airtight container in refrigerator up to 4 days.

Frequently Asked Questions

Reader questions and answers for this recipe will appear here.

Customize the One-Pan Herb-Crusted Turkey Breast with Roasted Brussels Sprouts and Cranberries to suit dietary preferences or ingredient availability with these healthy substitutions:

  • Turkey Breast: Swap with boneless skin-on chicken breast or thighs for a quicker, budget-friendly option.
  • Olive Oil: Use avocado oil, melted coconut oil, or another neutral oil based on flavor preference or dietary needs.
  • Dried Herbs (thyme, rosemary, sage): Replace with fresh herbs (use triple the amount) or an Italian seasoning blend for ease.
  • Brussels Sprouts: Substitute seasonal veggies like green beans, asparagus, or broccolini to keep dishes vibrant and fresh.
  • Fresh Cranberries: Use dried cranberries for sweeter chewiness or pomegranate seeds for tartness and color contrast.
  • Balsamic Vinegar and Honey/Maple Syrup: Swap for apple cider vinegar and agave nectar, or omit sweeteners for lower sugar content.

These options preserve the recipe’s ease, nutritional balance, gluten-free and dairy-free suitability, budget-friendly nature, and one-pan meal convenience for family-friendly dinners.

Pan Or Pot Required

This recipe is a convenient one-pan meal that combines herb-crusted turkey breast with roasted Brussels sprouts and cranberries for easy preparation and minimal cleanup. Use a large rimmed baking sheet or sheet pan that comfortably fits all ingredients without overcrowding. The rimmed edges help contain drippings and prevent spills during roasting at 400°F (200°C).

Choose a sturdy, heavy-duty baking sheet to ensure even heating and durability for optimal roasting. The one-pan method allows the turkey, vegetables, and cranberries to cook together, melding flavors and creating a delicious, wholesome meal perfect for busy weeknights or special occasions.

Cookware Size Guidance

For best results, use a large rimmed baking sheet or sheet pan measuring at least 15 x 10 inches (38 x 25 cm) with sides approximately 1 inch or higher. This size provides enough room to place the turkey breast, Brussels sprouts, and fresh cranberries in a single layer, promoting even roasting, caramelization, and air circulation.

A smaller pan may cause overcrowding leading to steaming rather than roasting, while a much larger pan can decrease flavor concentration. This recommended pan size supports hassle-free preparation for family dinners, holiday meals, or quick weeknight sheets pan dinners with easy cleanup and flavorful, tender results.

Cookware Swap Guidance

This herb-crusted turkey and vegetable recipe relies on a one-pan roasting technique using a large rimmed baking sheet or sheet pan. If you don't have this pan, suitable alternatives include:

  • Ovenproof roasting pan: Choose a medium to large roasting pan with sides wide enough to accommodate the turkey and vegetables in a single layer for even roasting.
  • Large cast iron skillet: Use a well-seasoned cast iron skillet with adequate diameter and sides to ensure proper browning and heat retention.
  • Glass or ceramic baking dish: A rimmed glass or ceramic dish suitable for roasting can be used, though cooking times may be slightly longer — monitor internal turkey temperature closely.

Avoid shallow pans without adequate sides to prevent spills and uneven cooking. Keeping ingredients spaced encourages caramelization and rich flavor development. This recipe complements categories such as One-Pan Chicken and Sheet Pan Dinners and fits well with tags like easy, familydinner, healthy, seasonal, and budget-friendly. For slow cooker or Instant Pot variations, check our Slow Cooker One-Pot and Instant Pot Recipes collections since roasting is key to the herb crust and caramelized flavor.

Leftovers Quality

This hearty one-pan herb-crusted turkey breast with roasted Brussels sprouts and cranberries makes excellent leftovers, storing well in the refrigerator for up to 4 days in an airtight container. It's perfect for meal prep or quick, nutritious lunches and dinners.

To reheat, warm turkey slices and vegetables gently in a preheated 325°F (165°C) oven for 10-15 minutes to preserve moisture and maintain the crispness of the Brussels sprouts. Alternatively, reheat in the microwave on medium power in short intervals, stirring vegetables occasionally to prevent sogginess.

This balanced meal delivers lasting flavors and nutrients, fitting gluten-free, dairy-free, budget-conscious, and family-friendly diets with ease, making it ideal for busy schedules without sacrificing taste or convenience.

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