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Sheet Pan Maple Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts

By PanPotPlates Test KitchenReviewed by PanPotPlates Editorial TeamPublished Apr 8, 2026 · Updated May 11, 2026
American 40 mins onepansheetpanquickeasyhealthyfamilydinnerbudget-friendlyseasonalroastedflavorful

Enjoy a healthy and easy sheet pan dinner with juicy pork tenderloin glazed in a zesty maple mustard sauce, roasted alongside perfectly caramelized Brussels sprouts. This quick, family-friendly recipe is budget-friendly and requires minimal cleanup.

Sheet Pan Maple Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts
Prep 10 min
Cook 30 min
Total 40 min
Servings 4
Difficulty easy
Cuisine American

Recipe Details

Prep10 min
Cook30 min
Total40 min
Servings4
Difficultyeasy
CuisineAmerican
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Ingredients

Servings 4
  • 1.5 pounds pork tenderloin, trimmed
  • 1 pound Brussels sprouts, trimmed and halved
  • 2 tablespoons olive oil
  • Salt and freshly ground black pepper, to taste
  • 3 tablespoons pure maple syrup
  • 2 tablespoons Dijon mustard
  • 1 tablespoon whole grain mustard
  • 2 cloves garlic, minced
  • 1 teaspoon apple cider vinegar
  • 1/2 teaspoon smoked paprika (optional)

Instructions

  1. Preheat oven to 400°F (200°C). Line a large rimmed sheet pan with parchment paper or lightly grease it.
  2. In a small bowl, whisk together maple syrup, Dijon mustard, whole grain mustard, minced garlic, apple cider vinegar, and smoked paprika until smooth. Set aside.
  3. Place pork tenderloin in the center of the prepared sheet pan. Brush half of the maple mustard glaze evenly over the pork.
  4. In a large bowl, toss halved Brussels sprouts with olive oil, salt, and pepper until well coated.
  5. Arrange Brussels sprouts around the pork in a single layer on the sheet pan.
  6. Roast in the preheated oven for 20 minutes, then carefully flip the pork and toss Brussels sprouts for even cooking.
  7. Brush the pork with the remaining glaze.
  8. Continue roasting for another 10-12 minutes, or until pork reaches an internal temperature of 145°F (63°C) and Brussels sprouts are tender and caramelized.
  9. Remove pork from oven and let rest for 5 minutes before slicing.
  10. Serve sliced pork tenderloin with roasted Brussels sprouts, drizzling pan juices over for extra flavor.

Frequently Asked Questions

Reader questions and answers for this recipe will appear here.

To personalize this Sheet Pan Maple Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts for dietary needs or ingredient availability, consider these swaps without compromising ease or flavor:

  • Pork Tenderloin: Replace with boneless chicken breasts or thighs for poultry options, or substitute plant-based pork alternatives for a vegetarian meal.
  • Brussels Sprouts: Swap with broccoli florets, green beans, or baby carrots that roast in similar times.
  • Olive Oil: Use avocado oil or melted coconut oil as healthy alternatives with unique flavors.
  • Pure Maple Syrup: Substitute honey or agave nectar, or a low-calorie maple-flavored syrup for sugar-free adaptations.
  • Mustards (Dijon and Whole Grain): Use yellow or spicy brown mustard per taste preference.
  • Apple Cider Vinegar: Replace with white wine vinegar or lemon juice for acidity.
  • Garlic: Fresh garlic can be replaced with garlic powder or roasted garlic paste.
  • For vegan and dairy-free needs, use marinated tofu or tempeh instead of pork and ensure maple syrup is pure.
  • For gluten-free versions, select certified gluten-free mustards and ingredients.

These substitutions keep the recipe quick, easy, family-friendly, and budget-conscious while accommodating a range of preferences.

Pan Or Pot Required

This recipe is a classic Sheet Pan Dinner, designed for effortless preparation and cleanup. Use a large rimmed sheet pan with raised edges to catch drippings and keep the pork tenderloin and Brussels sprouts contained while roasting. Lining the pan with parchment paper or a silicone baking mat helps prevent sticking and eases cleaning.

Cooking both the pork tenderloin and Brussels sprouts on a single sheet pan allows the maple mustard glaze flavors to meld beautifully, enhancing the roasted vegetables. This one-pan meal approach is ideal for quick, healthy, family-friendly, and budget-conscious dinners with minimal cleanup required.

No additional pots or pans are necessary. All mixing, glazing, and roasting happen on or with the sheet pan, saving time on prep and cleanup—a perfect option for busy weeknights.

Grab your preferred large sheet pan, line it, and enjoy a wholesome, flavorful one-pan meal!

Cookware Size Guidance

For this Sheet Pan Dinner serving 4 people, we recommend a large rimmed sheet pan at least 15x10 inches (38x25 cm). This surface area comfortably fits the 1.5-pound pork tenderloin in the center with enough room to spread Brussels sprouts in a single layer, ensuring even roasting and caramelization without overcrowding.

Using a pan that's too small may cause steaming rather than roasting, leading to softer textures and less flavor. A pan too large can result in uneven cooking or drying out.

If a 15x10-inch pan isn't available, select one with similar surface area and raised edges to hold glaze and juices during cooking. Line it with parchment paper or lightly grease for easier cleanup—perfect for a quick, family-friendly meal.

Cookware Swap Guidance

This Sheet Pan Maple Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts is a quick, easy, and healthy Sheet Pan Dinner ideal for family meals. If a sheet pan isn't available, consider these cookware substitutions that keep the recipe convenient and flavorful:

  • Roasting Pan with Rack: Use for even roasting; arrange Brussels sprouts separately to avoid overcrowding.
  • Large Oven-Safe Casserole or Baking Dish: Suitable if you can lay ingredients in a single layer—though caramelization may be slightly less crisp.
  • Oven-Safe Skillet (Cast Iron or Stainless Steel): Sear pork on the stovetop, then roast with Brussels sprouts in the skillet for a one-pan method.
  • Baking Tray or Pizza Stone: Line with parchment or foil to approximate sheet pan roasting surface.

Note that cookware with higher sides may trap moisture, reducing crispness of Brussels sprouts. To promote caramelization, avoid overcrowding and consider broiling briefly at the end if needed. These swaps preserve the recipe’s quick, easy, and healthy qualities.

Leftovers Quality

This sheet pan pork tenderloin with maple mustard glaze and roasted Brussels sprouts makes delicious leftovers. Store cooled portions in an airtight container refrigerated for up to 3 to 4 days.

For best results, gently reheat in the microwave on medium power in 30-second intervals, stirring Brussels sprouts occasionally. Alternatively, warm in a 325°F (165°C) oven for 10-15 minutes, covered loosely with foil to retain moisture and prevent drying.

Be careful not to overcook when reheating to keep pork juicy and Brussels sprouts caramelized yet tender.

You can also freeze leftovers wrapped in freezer-safe packaging for up to 2 months. Thaw overnight in the refrigerator before reheating for optimal texture and flavor.

These tips ensure you can enjoy this healthy, easy, and budget-friendly one-pan meal beyond the first dinner.

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